Multivariate and Univariate Analysis of Continuous Arterial Spin Labeling Perfusion MRI in Alzheimer's Disease
نویسندگان
چکیده
منابع مشابه
Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's disease.
Continuous arterial spin labeling (CASL) magnetic resonance imaging (MRI) was combined with multivariate analysis for detection of an Alzheimer's disease (AD)-related cerebral blood flow (CBF) covariance pattern. Whole-brain resting CBF maps were obtained using spin echo, echo planar imaging (SE-EPI) CASL in patients with mild AD (n=12, age=70.7+/-8.7 years, 7 males, modified Mini-Mental State ...
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Perfusion is a physiological parameter that refers to the delivery of oxygen and nutrients to tissues via the flow of blood (1). Cerebral blood flow (CBF) is generally quantified in terms of milliliters of blood per gram of tissue per second ml/g/sec (2). Perfusion measurements provide information regarding tissue viability and function, and are therefore of fundamental significance in the fiel...
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The first implementation of real-time acquisition and analysis of arterial spin labeling-based functional magnetic resonance imaging time series is presented in this article. The implementation uses a pseudo-continuous labeling scheme followed by a spiral k-space acquisition trajectory. Real-time reconstruction of the images, preprocessing, and regression analysis of the functional magnetic res...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2007
ISSN: 0271-678X,1559-7016
DOI: 10.1038/sj.jcbfm.9600570